Colonia Nápoles is a colonia in Benito Juárez, Mexico City in the North central area of the metropolis. Along with Colonia Del Valle, it's among the most representative of Mid-Century neighborhoods of Mexico City.

The World Trade Center Mexico City, commonly known by its former name, Hotel de México, is a building complex located in the wealthy neighborhood of Colonia Nápoles in central Mexico City. Its most famous and recognizable feature is the 50-story, 172 metres (564 ft) high Torre WTC, the biggest building in the local area. It is the third tallest building in Mexico City when including antenna, and at its roof height, it stands 218 metres (715 ft).