Columbia is a city in the U.S. state of Missouri. It is the county seat of Boone County and home to the University of Missouri. Founded in 1821, it is the principal city of the three-county Columbia metropolitan area. It is Missouri's fourth most populous with an estimated 128,555 residents in 2022.

Missouri is a landlocked state in the Midwestern region of the United States. Ranking 21st in land area, it borders Iowa to the north, Illinois, Kentucky and Tennessee to the east, Arkansas to the south and Oklahoma, Kansas, and Nebraska to the west. In the south are the Ozarks, a forested highland, providing timber, minerals, and recreation. The Missouri River, after which the state is named, flows through the center and into the Mississippi River, which makes up the eastern border. With over six million residents, it is the 18th-most populous state of the country. The largest urban areas are St. Louis, Kansas City, Springfield, and Columbia; the capital is Jefferson City.