Columbus Air Force Base is a United States Air Force base located in Columbus, Mississippi. The host unit at Columbus AFB is the 14th Flying Training Wing , which is a part of Air Education and Training Command (AETC).

Columbus is a city in and the county seat of Lowndes County, on the eastern border of Mississippi, United States, located primarily east, but also north and northeast of the Tombigbee River, which is also part of the Tennessee-Tombigbee Waterway. It is approximately 146 miles (235 km) northeast of Jackson, 92 miles (148 km) north of Meridian, 63 miles (101 km) south of Tupelo, 60 miles (97 km) northwest of Tuscaloosa, Alabama, and 120 miles (193 km) west of Birmingham, Alabama.