Combined Task Force 150 (CTF-150) is a multinational coalition naval task force working under the 34-nation coalition of Combined Maritime Forces and is based in Bahrain established to monitor, board, inspect, and stop suspect shipping to pursue the "War on Terror" and in the Horn of Africa region (HOA) includes operations in the North Arabia Sea to support operations in the Indian Ocean. These activities are referred to as Maritime Security Operations (MSO).

The war on terror, officially the Global War on Terrorism (GWOT), is a global military campaign initiated by the United States following the September 11 attacks and is the most recent global conflict spanning multiple wars. The main targets of the campaign are militant Islamist movements like Al-Qaeda, Taliban and their allies. Other major targets included the Ba'athist regime in Iraq, which was deposed in an invasion in 2003, and various militant factions that fought during the ensuing insurgency. After its territorial expansion in 2014, the Islamic State militia has also emerged as a key adversary of the United States.