The Commander-in-Chief, Africa was the last title of a Royal Navy's formation commander located in South Africa from 1795 to 1939. Under varying titles, it was one of the longest-lived formations of the Royal Navy. It was also often known as the Cape of Good Hope Station.

The West Africa Squadron, also known as the Preventative Squadron, was a squadron of the British Royal Navy whose goal was to suppress the Atlantic slave trade by patrolling the coast of West Africa. Formed in 1808 after the British Parliament passed the Slave Trade Act 1807 and based out of Portsmouth, England, it remained an independent command until 1856 and then again from 1866 to 1867.