The Commander-in-Chief, Plymouth, was a senior commander of the Royal Navy for hundreds of years. Plymouth Command was a name given to the units, establishments, and staff operating under the admiral's command. Between 1845 and 1896, this office was renamed Commander-in-Chief, Devonport. The Commanders-in-Chief were based in what is now Hamoaze House, Devonport, Plymouth, from 1809 to 1934 and then at Admiralty House, Mount Wise, Devonport, from 1934 until 1996.

Admiral Thomas Graves, 1st Baron Graves, KB was a British officer of the Royal Navy and a colonial official. He served in the Seven Years' War and the American War of Independence. He was also the Commodore-Governor of Newfoundland for a period of time.