Commissariat Store is a heritage-listed storehouse at 115–127 William Street, Brisbane City, City of Brisbane, Queensland, Australia. It is bordered by William Street, Queen's Wharf Road and the Brisbane River, and is the birthplace of Queensland. It was designed by William John Dumaresq and built from 1828 to 1913 by convict labour under the direction of Captain Logan as a permanent Commissariat Store for the Moreton Bay penal settlement. It is also known as Government Stores, State Stores Building, and Colonial Store. It was added to the Queensland Heritage Register on 21 October 1992.

William Street is a small, relatively quiet road in the uptown part of the Brisbane central business district. The street is historically significant to the city's early development as a penal colony. The first convict buildings were built along William Street in 1825.