The commissioning of the Twelve Apostles is an episode in the ministry of Jesus that appears in all three Synoptic Gospels: Matthew 10:1–4, Mark 3:13–19 and Luke 6:12–16. It relates the initial selection of the Twelve Apostles among the disciples of Jesus.

The ministry of Jesus, in the canonical gospels, begins with his baptism near the River Jordan by John the Baptist, and ends in Jerusalem in Judea, following the Last Supper with his disciples. The Gospel of Luke states that Jesus was "about 30 years of age" at the start of his ministry. A chronology of Jesus typically sets the date of the start of his ministry at around AD 27–29 and the end in the range AD 30–36.