Complexin refers to a one of a small set of eukaryotic cytoplasmic neuronal proteins which binds to the SNARE protein complex with a high affinity. These are called synaphin 1 and 2. In the presence o
3-D structure of the Complexin/SNARE complex
The active zone or synaptic active zone is a term first used by Couteaux and Pecot-Dechavassinein in 1970 to define the site of neurotransmitter release. Two neurons make near contact through structur
The vesicle release machinery.
The presynaptic active zone and the synaptic vesicle cycle
A diagram showing the change in membrane capacitance before (top) and after (middle and bottom) vesicle fusion.