Route 49 is a Connecticut state highway from Route 2 in Stonington to Route 14A in Sterling, in the southeast part of the state. It is a scenic route that runs 21.74 miles (34.99 km) through the Pachaug State Forest.

Route 2 is a 58.03-mile (93.39 km) state highway in Hartford and New London counties in Connecticut. It is a primary state route, with a freeway section connecting Hartford to Norwich and following surface roads to Stonington. The entire freeway section of Route 2 west of Route 169 is also known as the Veterans of Foreign Wars Memorial Highway Though it is labelled an east-west highway, it follows a northwest-southeast route, with large sections of the highway running north-south throughout its duration.