The Cooper River is a mainly tidal river in the U.S. state of South Carolina. The cities of Mt. Pleasant, Charleston, North Charleston, Goose Creek, Moncks Corner, and Hanahan are located along the river. Short and wide, the river is joined first by the blackwater East Branch and then farther downstream at the tidal Wando River. Almost immediately thereafter, the Cooper River widens into its estuary and unites with the Ashley River to form the Charleston Harbor.

Mount Pleasant is a large suburban town in Charleston County, South Carolina, United States. In the Lowcountry, it is the fourth-most populous municipality in South Carolina, and for several years was one of the state's fastest-growing areas, doubling in population between 1990 and 2000. The population was 90,801 at the 2020 census. It is part of the Charleston metropolitan area.