Cranberry Lake is on the east branch of the Oswegatchie River in the Adirondack Park in New York in the United States. It is the third largest lake in the Adirondack Park. About 75 percent of the shoreline is owned by the State of New York. The 118,000-acre (480 km2) Five Ponds Wilderness Area abuts its south shore, and the Cranberry Lake Wild Forest covers much of its remaining shoreline.

The Oswegatchie River is a 137-mile-long (220 km) river in northern New York that flows from the Adirondack Mountains north to the Saint Lawrence River. The Oswegatchie River begins at Partlow Lake in Hamilton County, New York. The river continues through Cranberry Lake which was 'doubled in size' through construction of a dam in the late 1860s. The river continues from the dam to Gouverneur, to near Talcville in St. Lawrence County, where it joins the West Branch. Much of it is within Adirondack State Park. The city of Ogdensburg developed at the mouth of the river at its confluence with the St. Lawrence.