Crescent City is the only incorporated city in Del Norte County, California; it is also the county seat. Named for the crescent-shaped stretch of sandy beach south of the city, Crescent City had a total population of 6,673 in the 2020 census, down from 7,643 in the 2010 census.

U.S. Route 101 (US 101) is a major north–south United States Numbered Highway, stretching from Los Angeles, California, to Tumwater, Washington. The California portion of US 101 is one of the last remaining and longest U.S. Routes still active in the state, and the longest highway of any kind in California. US 101 was also one of the original national routes established in 1926. Significant portions of US 101 between the Los Angeles area and the San Francisco Bay Area follow El Camino Real, the commemorative route connecting the former Alta California's 21 missions.