The Critics' Choice Movie Award for Best Actress is an award given out at the annual Critics' Choice Movie Awards. The awards are presented by the Broadcast Film Critics Association (BFCA), and was first presented in 1995. There were no official nominees announced until 2001. There are currently six nominees annually, and there have been three ties in this category. Cate Blanchett, Jessica Chastain, Frances McDormand, Julianne Moore, Natalie Portman, Meryl Streep, and Hilary Swank are the only actresses who have received this award more than once, with two wins each.

Poor Things is a 2023 film directed by Yorgos Lanthimos and written by Tony McNamara, based on the 1992 novel by Alasdair Gray. A co-production between Ireland, the United Kingdom, and the United States, the film stars Emma Stone, Mark Ruffalo, Willem Dafoe, Ramy Youssef, Christopher Abbott, and Jerrod Carmichael. It focuses on Bella Baxter, a fetus in the body of an adult woman in Victorian London who is saved from her mother's suicide via brain transplant and embarks on an odyssey of self-discovery.