Cruella de Vil is a fictional character in British author Dodie Smith's 1956 novel The Hundred and One Dalmatians. A pampered and glamorous London heiress and fashion designer, she appears in Walt Disney Productions' animated feature film, One Hundred and One Dalmatians (1961), voiced by Betty Lou Gerson; in Disney's 101 Dalmatians II: Patch's London Adventure (2003), voiced by Susanne Blakeslee; in Disney's live-action 101 Dalmatians (1996) and 102 Dalmatians (2000), portrayed by Glenn Close; as well as Cruella (2021), portrayed by Emma Stone; and in many other Disney sequels and spin-offs.

One Hundred and One Dalmatians is a 1961 American animated adventure comedy film produced by Walt Disney Productions with distribution by Buena Vista Distribution. Adapted from Dodie Smith's 1956 novel of the same name, the film was directed by Hamilton Luske, Clyde Geronimi, and Wolfgang Reitherman from a script by Bill Peet. It features the voice talents of Rod Taylor, J. Pat O'Malley, Betty Lou Gerson, Martha Wentworth, Ben Wright, Cate Bauer, Dave Frankham, and Fred Worlock.