Cubana de Aviación S.A., commonly known as Cubana, is Cuba's flag carrier, as well as the country's largest airline. It was founded in October 1929, becoming one of the earliest airlines to emerge in Latin America. It has its corporate headquarters in Havana, and its main base is located at José Martí International Airport. Originally a subsidiary of Pan American World Airways and later a private company owned by Cuban investors, Cubana has been wholly owned by the Cuban government since May 1959.

Clement Melville Keys was a financier who was involved in the establishment of many aviation companies including Curtiss-Wright, China National Aviation Corporation, North American Aviation and TWA. He has been called "the father of commercial aviation in America."