Cucumis melo, also known as melon, is a species of Cucumis that has been developed into many cultivated varieties. The fruit is a pepo. The flesh is either sweet or bland, with or without a musky aroma, and the rind can be smooth, ribbed, wrinkled, or netted. In North America, the sweet-flesh varieties are often collectively called muskmelon, including the musky netted-rind varieties and the inodorous smooth-rind varieties, and cantaloupe usually refers to the former type. However, muskmelon in a narrow sense only refers to the musky netted-rind type, also known as North American cantaloupe, while the true cantaloupe is the European type with ribbed and often warty rind that is seldom grown in North America.

Cucumis is a genus of twining, tendril-bearing plants in the family Cucurbitaceae which includes the cucumber, true melons, the horned melon, and the West Indian gherkin.