Cuyahoga County is a large urban county located in the northeastern part of the U.S. state of Ohio. The county seat and largest city is Cleveland. As of the 2020 census, its population was 1,264,817, making it the second-most populous county in the state.

The region Northeast Ohio, in the US state of Ohio, in its most expansive usage contains six metropolitan statistical areas: Cleveland–Elyria, Akron, Canton–Massillon, Youngstown–Warren, Mansfield, and Weirton–Steubenville along with eight micropolitan statistical areas. Most of the region is considered either part of the Cleveland–Akron–Canton, OH Combined Statistical Area and media market or the Youngstown–Warren, OH–PA Combined Statistical Area and media market. In all, the region is home to: 4,502,460 residents. It is also a part of the Great Lakes megalopolis, containing over 54 million people. Northeast Ohio also includes most of the area known historically as the Connecticut Western Reserve.