Cyprus participated in the Eurovision Song Contest 2021 in Rotterdam, the Netherlands. The Cypriot broadcaster Cyprus Broadcasting Corporation (CyBC) internally selected Elena Tsagrinou as its representative with the song "El Diablo". "El Diablo" was written and composed by Thomas Stengaard, Laurell Barker, Oxa, and Jimmy Thörnfeldt. Cyprus performed 8th in the first semi-final of the Eurovision Song Contest 2021, held on 18 May 2021, and placed 6th, receiving 170 points. The entry qualified for the final held four days later, where the nation placed 16th with 94 points.

Azerbaijan participated in the Eurovision Song Contest 2021 with the song "Mata Hari" written by Amy van der Wel, Josh Earl, Luuk van Beers and Tony Cornelissen. The song was performed by Efendi, who was internally selected by the Azerbaijani broadcaster İctimai Television (İTV) to represent the nation at the 2021 contest in Rotterdam, Netherlands, after she was due to compete in the 2020 contest with "Cleopatra" before the 2020 event's cancellation. Efendi's selection as the Azerbaijani Eurovision entrant was announced on 20 March 2020, while the song "Mata Hari" was presented to the public on 15 March 2021.