Cyrene (Latin) or Kyrene, pronounced variously as sy-REE-nee or ky-REE-nee, was a figure in Greek mythology considered the etymon of the Greek colony of Cyrene in eastern Libya in North Africa. She was said to have been a Thessalian princess who became the queen of Cyrene, founded and named in her honor by Apollo. The story is entirely apocryphal, the city having been founded by settlers from Thera.

In Greek mythology, Chiron was held to be the superlative centaur amongst his brethren since he was called the "wisest and justest of all the centaurs".