Cytogenetics
Videos
Cytogenetics is essentially a branch of genetics, but is also a part of cell biology/cytology, that is concerned with how the chromosomes relate to cell behaviour, particularly to their behaviour duri
Philadelphia translocation t(9;22)(q34;q11.2) seen in chronic myelogenous leukemia.
Interphase cells positive for a t(9;22) rearrangement
Fluorescence in situ hybridization is a molecular cytogenetic technique that uses fluorescent probes that bind to specific parts of a nucleic acid sequence with a high degree of sequence complementari
Cytogenetics
…Techniques used include karyotyping, analysis of G-banded chromosomes, other cytogenetic banding techniques, as well as molecular cytogenetics such as fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH). Chromosomes were first observed in plant cells by Carl Nägeli in 1842. Their behavior in animal…
Multiplex RNA visualization in cells using ViewRNA FISH Assays
ViewRNA detection of miR-133(green) and myogenin mRNA (red) in C2C12 differentiating cells
Scheme of the principle of the FISH Experiment to localize a gene in the nucleus.
Microfluidic chip that lowered the cost-per-test of FISH by 90%.