Daffy Duck's Quackbusters is a 1988 animated compilation film featuring classic Warner Bros. Cartoons shorts and animated bridging sequences, starring Daffy Duck. The film was released to theaters by Warner Bros. on September 24, 1988. It was the final theatrical production in which Mel Blanc provided the voices of the various Looney Tunes characters before his death in July 1989.

Daffy Duck is a fictional character created by animators Tex Avery and Bob Clampett for Leon Schlesinger Productions. Styled as an anthropomorphic black duck, he has appeared in cartoon series such as Looney Tunes and Merrie Melodies, in which he is usually depicted as a foil for either Bugs Bunny, Porky Pig or Speedy Gonzales. He was one of the first of the new "screwball" characters that emerged in the late 1930s to replace traditional everyman characters who were more popular earlier in the decade, such as Mickey Mouse, Porky Pig, and Popeye.