Danville is a city in and the county seat of Vermilion County, Illinois, United States. As of the 2020 census, its population was 29,204. It is the principal city of the Danville metropolitan area.

Interstate 74 (I-74) is an Interstate Highway in the Midwestern and Southeastern United States. Its western end is at an interchange with I-80 in Davenport, Iowa ; the eastern end of its Midwest segment is at an interchange with I-75 in Cincinnati, Ohio. The major cities that I-74 connects to include Davenport, Iowa; Peoria, Illinois; Bloomington, Illinois; Champaign, Illinois; Indianapolis, Indiana; and Cincinnati, Ohio. I-74 also exists as several disconnected sections of highways in North Carolina.