The Darwin–Wedgwood family are members of two connected families, each noted for particular prominent 18th-century figures: Erasmus Darwin, a physician and natural philosopher, and Josiah Wedgwood FRS, a noted potter and founder of the eponymous Josiah Wedgwood & Sons pottery company. The Darwin and Wedgwood families were on friendly terms for much of their history and members intermarried, notably Charles Darwin, who married Emma Wedgwood.

Erasmus Robert Darwin was an English physician. One of the key thinkers of the Midlands Enlightenment, he was also a natural philosopher, physiologist, slave-trade abolitionist, inventor, and poet.