Davenport Bank and Trust Company was the leading bank of the Quad Cities metropolitan area for much of the 20th century and for the surrounding region of eastern Iowa and western Illinois. It was once Iowa's largest commercial bank, and the headquarters building has dominated the city's skyline since it was constructed in 1927 at the corner of Third and Main Streets in downtown Davenport, Iowa. It was acquired by Norwest Bank of Minneapolis in 1993 and now operates as part of Wells Fargo following a 1998 merger of the two financial institutions. The historic building was listed on the National Register of Historic Places in 1983 under the name of its predecessor financial institution American Commercial and Savings Bank. In 2016 the National Register approved a boundary increase with the Davenport Bank and Trust name. It was included as a contributing property in the Davenport Downtown Commercial Historic District in 2020. It remains the tallest building in the Quad Cities, and is today known as Davenport Bank Apartments as it has been redeveloped into a mixed-use facility housing commercial, office, and residential space.

Davenport is a city in and the county seat of Scott County, Iowa, United States. Located along the Mississippi River on the eastern border of the state, it is the largest of the Quad Cities, a metropolitan area with a population of 384,324 and a combined statistical area population of 474,019, ranking as the 147th-largest MSA and 91st-largest CSA in the nation. According to the 2020 census, the city had a population of 101,724, making it Iowa's third-most populous city after Des Moines and Cedar Rapids. Davenport was founded on May 14, 1836, by Antoine Le Claire and named for his friend George Davenport.