De-Loused in the Comatorium is the debut studio album by American progressive rock band the Mars Volta, released on June 24, 2003, on Gold Standard Laboratories and Universal Records. Based on a short story written by lead singer Cedric Bixler-Zavala and sound manipulation artist Jeremy Ward, the concept album is an hour-long tale of Cerpin Taxt, a man who enters a week-long coma after overdosing on a mixture of morphine and rat poison. The story of Cerpin Taxt alludes to the death of El Paso, Texas artist—and Bixler-Zavala's friend—Julio Venegas (1972–1996).

The Mars Volta is an American progressive rock band from El Paso, formed in 2001. The band's only constant members are Omar Rodríguez-López and Cedric Bixler-Zavala, whose partnership forms the core of the band. The band's current line-up also includes founding member Eva Gardner (bass), Omar's brother Marcel Rodriguez-Lopez, Leo Genovese and Linda-Philomène Tsoungui (drums).