DeLaSalle High School is a Catholic, college preparatory high school in Minneapolis, Minnesota. It is located on Nicollet Island.

Nicollet Island is an island in the Mississippi River just north of Saint Anthony Falls in central Minneapolis, Minnesota. According to the United States Census Bureau the island has a land area of 194,407 square metres (0.075 sq mi) and a 2000 census population of 144 persons. The island makes up a large part of the city-designated Nicollet Island/East Bank neighborhood. The island is named for cartographer Joseph Nicollet, who mapped the Upper Mississippi in the 1830s.