De La Salle College is a Catholic private school for boys in the Melbourne suburb of Malvern. The college was founded in 1912 by the De La Salle Brothers, a religious order based on the teachings of Jean-Baptiste de la Salle, and is a member of the Associated Catholic Colleges. The college consists of three campuses located in Malvern and Malvern East. De La Salle's sister school is Star of the Sea College.

Malvern ( ) is a suburb of Melbourne, Victoria, Australia, 8 km south-east of Melbourne's Central Business District, located within the City of Stonnington local government area. Malvern recorded a population of 9,929 at the 2021 census.