Cleopatra VII, the last ruler of Ptolemaic Egypt, died on either 10 or 12 August, 30 BC, in Alexandria, when she was 39 years old. According to popular belief, Cleopatra killed herself by allowing an asp to bite her, but according to the Roman-era writers Strabo, Plutarch, and Cassius Dio, Cleopatra poisoned herself using either a toxic ointment or by introducing the poison with a sharp implement such as a hairpin. Modern scholars debate the validity of ancient reports involving snakebites as the cause of death and whether she was murdered. Some academics hypothesize that her Roman political rival Octavian forced her to kill herself in a manner of her choosing. The location of Cleopatra's tomb is unknown. It was recorded that Octavian allowed for her and her husband, the Roman politician and general Mark Antony, who stabbed himself with a sword, to be buried together properly.

Cleopatra VII Thea Philopator was Queen of the Ptolemaic Kingdom of Egypt from 51 to 30 BC, and its last active ruler. A member of the Ptolemaic dynasty, she was a descendant of its founder Ptolemy I Soter, a Macedonian Greek general and companion of Alexander the Great. After the death of Cleopatra, Egypt became a province of the Roman Empire, marking the end of the last Hellenistic-period state in the Mediterranean and of the age that had lasted since the reign of Alexander. Her first language was Koine Greek, and she was the only known Ptolemaic ruler to learn the Egyptian language.