Debrecen International Airport is the international airport of Debrecen in the Hajdú-Bihar County of Hungary. It is the second largest airport in Hungary, after Budapest and ahead of Hévíz–Balaton. Debrecen is the second largest city in Hungary, after Budapest and ahead of Szeged. DEB is located 5 km (3.1 mi) south southwest of the city center and also easily accessible to adjacent regions of Romania and Ukraine.

Debrecen is Hungary's second-largest city, after Budapest, the regional centre of the Northern Great Plain region and the seat of Hajdú-Bihar County. A city with county rights, it was the largest Hungarian city in the 18th century and it is one of the Hungarian people's most important cultural centres. Debrecen was also the capital city of Hungary during the revolution in 1848–1849. During the revolution, the dethronement of the Habsburg dynasty was declared in the Reformed Great Church. The city also served as the capital of Hungary by the end of World War II in 1944–1945. It is home to the University of Debrecen.