Denham Springs High School is a public high school located in Denham Springs, Louisiana, United States. Denham Springs High School is a part of the Livingston Parish School System and was founded in 1897 as a school for the residents of Denham Springs, a city located in Livingston Parish. The school is located on Louisiana Highway 16, adjacent to Denham Springs Freshman High. The school's location makes it prone to flooding. This was the case when flooding devastated the area in 2016, and resulted in students having to travel to nearby Live Oak High School for classes.

Denham Springs is a city in Livingston Parish, Louisiana, United States. The 2010 U.S. census placed the population at 10,215, up from 8,757 at the 2000 U. S. census. At the 2020 United States census, 9,286 people lived in the city. The city is the largest area of commercial and residential development in Livingston Parish. Denham Springs and Walker are the only parish municipalities classified as cities. The area has been known as Amite Springs, Hill's Springs, and Denham Springs.