The Department of Computer Science is the computer science department of the University of Oxford, England, which is part of the university's Mathematical, Physical and Life Sciences Division. It was founded in 1957 as the Computing Laboratory. By 2014 the staff count was 52 members of academic staff and over 80 research staff. The 2019, 2020 and 2021 Times World University Subject Rankings places Oxford University 1st in the world for Computer Science. Oxford University is also the top university for computer science in the UK and Europe according to Business Insider. The 2020 QS University Subject Rankings places The University of Oxford 5th in the world for Computer Science.

Christopher S. Strachey was a British computer scientist. He was one of the founders of denotational semantics, and a pioneer in programming language design and computer time-sharing. He has also been credited as possibly being the first developer of a video game. He was a member of the Strachey family, prominent in government, arts, administration, and academia.