The Department of Health is the executive department of the government of the Philippines responsible for ensuring access to basic public health services by all Filipinos through the provision of quality health care, the regulation of all health services and products. It is the government's over-all technical authority on health. It has its headquarters at the San Lazaro Compound, along Rizal Avenue in Manila.

Rizal Avenue, also known as Avenida or Avenida Rizal, is one of Manila's main thoroughfares running from its Santa Cruz and Quiapo districts to the Bonifacio Monument (Monumento) Circle in Caloocan. Named after the national hero José Rizal, it is a part of Radial Road 9 (R-9). The LRT Line 1 elevated railroad is built above the street in its entire length, and several jeepneys ply the area taking passengers from Caloocan, Quezon City, and Valenzuela. Most of the street is within Santa Cruz, Manila. By the 1960s, economic activities shifted from Binondo to Makati. The avenue forms part of National Route 150 (N150) of the Philippine highway network.