Deptford is an area on the south bank of the River Thames in southeast London, in the Royal Borough of Greenwich and London Borough of Lewisham. It is named after a ford of the River Ravensbourne. From the mid 16th century to the late 19th it was home to Deptford Dockyard, the first of the Royal Dockyards. This was a major shipbuilding dock and attracted Peter the Great to come and study shipbuilding. Deptford and the docks are associated with the knighting of Sir Francis Drake by Queen Elizabeth I aboard the Golden Hind, the legend of Sir Walter Raleigh laying down his cape for Elizabeth, Captain James Cook's third voyage aboard HMS Resolution, and the mysterious apparent murder of Christopher Marlowe in a house along Deptford Strand.

Christopher Marlowe, also known as Kit Marlowe, was an English playwright, poet, and translator of the Elizabethan era. Marlowe is among the most famous of the Elizabethan playwrights. Based upon the "many imitations" of his play Tamburlaine, modern scholars consider him to have been the foremost dramatist in London in the years just before his mysterious early death. Some scholars also believe that he greatly influenced William Shakespeare, who was baptised in the same year as Marlowe and later succeeded him as the preeminent Elizabethan playwright. Marlowe was the first to achieve critical reputation for his use of blank verse, which became the standard for the era. His plays are distinguished by their overreaching protagonists. Themes found within Marlowe's literary works have been noted as humanistic with realistic emotions, which some scholars find difficult to reconcile with Marlowe's "anti-intellectualism" and his catering to the prurient tastes of his Elizabethan audiences for generous displays of extreme physical violence, cruelty, and bloodshed.