The deputy prime minister of the Netherlands is the official deputy of the head of government of the Netherlands. In the absence of the prime minister of the Netherlands the deputy prime minister takes over his functions, such as chairing the Cabinet of the Netherlands and the Council of Ministers of the Netherlands. Conventionally, all of the junior partners in the coalition get one deputy, and the deputies are ranked according to the size of their respective parties. The incumbent deputy prime ministers are Rob Jetten of the Democrats 66 serving as Minister for Climate and Energy, Karien van Gennip of the Christian Democratic Appeal serving as Minister of Social Affairs and Employment and Carola Schouten of the Christian Union serving as Minister for Welfare and Civic Engagement.

The prime minister of the Netherlands is the head of the executive branch of the Government of the Netherlands. Although the monarch is the de jure head of government, the prime minister de facto occupies this role as the officeholder chairs the Council of Ministers and coordinates its policy with the rest of the cabinet. In his role as head of government, the prime minister also represents the Netherlands in the European Council. The current acting prime minister, Mark Rutte, has been in the position since 14 October 2010, with his fourth cabinet being inaugurated on 10 January 2022. He resigned his position on 7 July 2023 and until a new prime minister is sworn in after the 2023 Dutch general election, he will serve in a demissionary capacity.