Dere Street or Deere Street is a modern designation of a Roman road which ran north from Eboracum (York), crossing the Stanegate at Corbridge and continuing beyond into what is now Scotland, later at least as far as the Antonine Wall. It was the Romans' major route for communications and supplies to the north and to Scotland. Portions of its route are still followed by modern roads, including the A1(M), the B6275 road through Piercebridge, where Dere Street crosses the River Tees, and the A68 north of Corbridge in Northumberland.

Eboracum was a fort and later a city in the Roman province of Britannia. In its prime it was the largest town in northern Britain and a provincial capital. The site remained occupied after the decline of the Western Roman Empire and ultimately developed into the present-day city of York, in North Yorkshire, England.