Desilu Productions, Inc. was an American television production company founded and co-owned by husband and wife Desi Arnaz and Lucille Ball. The company is best known for shows such as I Love Lucy, The Lucy Show, Mannix, The Untouchables, Mission: Impossible and Star Trek. Until 1962, Desilu was the second-largest independent television production company in the United States, behind MCA's Revue Studios, until MCA bought Universal Pictures and Desilu became and remained the number-one independent production company, until Ball sold it to Gulf and Western Industries in 1968.

Desiderio Alberto Arnaz y de Acha III, known as Desi Arnaz, was a Cuban-American actor, musician, producer and bandleader. He played Ricky Ricardo on the American television sitcom I Love Lucy, in which he co-starred with his wife Lucille Ball. Arnaz and Ball are credited as the innovators of the syndicated rerun, which they pioneered with the I Love Lucy series.