"Desire" is a song by Irish rock band U2 and the third track on their 1988 album, Rattle and Hum. It was released as the album's lead single on 19 September 1988, and became the band's first number-one single in the United Kingdom and Australia. It reached number three on the Billboard Hot 100 in the United States, and topped both the Modern Rock Tracks and Mainstream Rock Tracks charts, making it the first song to reach number one on both charts simultaneously. It reached number two on the Dutch Top 40. At the 31st Annual Grammy Awards, "Desire" won the 1988 Grammy Award for Best Rock Performance by a Duo or Group with Vocal.

U2 are an Irish rock band formed in Dublin in 1976. The group consists of Bono, the Edge, Adam Clayton, and Larry Mullen Jr.. Initially rooted in post-punk, U2's musical style has evolved throughout their career, yet has maintained an anthemic quality built on Bono's expressive vocals and the Edge's chiming, effects-based guitar sounds. Bono's lyrics, often embellished with spiritual imagery, focus on personal and sociopolitical themes. Popular for their live performances, the group have staged several elaborate tours over their career.