Destination Tokyo is a 1943 black and white American submarine war film. The film was directed by Delmer Daves in his directorial debut, and the screenplay was written by Daves and Albert Maltz, based on an original story by former submariner Steve Fisher. The film stars Cary Grant and John Garfield and features Dane Clark, Robert Hutton, and Warner Anderson, along with John Ridgely, Alan Hale Sr. and William Prince.

The submarine film is a subgenre of war film in which the majority of the plot revolves around a submarine below the ocean's surface. Films of this subgenre typically focus on a small but determined crew of submariners battling against enemy submarines or submarine-hunter ships, or against other problems ranging from disputes amongst the crew, threats of mutiny, life-threatening mechanical breakdowns, or the daily difficulties of living on a submarine.