Destroy All Humans! Path of the Furon is an action-adventure video game developed by American studio Sandblast Games and published by THQ. The game is set in the 1970s and is the fourth installment in the original Destroy All Humans! franchise. It was released December 1, 2008 in North America for the Xbox 360. Path of the Furon expands on the open world format of the previous Destroy All Humans! games, with five open worlds on the ground and in the air to obliterate with weapons and alien powers.

Richard Steven Horvitz is an American actor and comedian, best known for his voice work in animation and video games. His voice credits include the original Alpha 5 on Mighty Morphin Power Rangers, Power Rangers Zeo and Power Rangers Turbo, Razputin Aquato in Psychonauts, Kaos in Skylanders, Billy and his father Harold in Grim & Evil and The Grim Adventures of Billy & Mandy, Grey Matter in Ben 10, Rodney in Squirrel Boy, Daggett in The Angry Beavers, Zim in Invader Zim, Orthopox in Destroy All Humans!, the Zoni in Ratchet & Clank, Bumble in Kinectimals, the Space Weaver in Broken Age, Kanchomé in Zatch Bell!, and Moxxie in Helluva Boss.