The Detroit Institute of Arts (DIA) is a museum institution located in Midtown Detroit, Michigan. It has one of the largest and most significant art collections in the United States. With over 100 galleries, it covers 658,000 square feet (61,100 m2) with a major renovation and expansion project completed in 2007 that added 58,000 square feet (5,400 m2). The DIA collection is regarded as among the top six museums in the United States with an encyclopedic collection which spans the globe from ancient Egyptian and European works to contemporary art. Its art collection is valued in billions of dollars, up to $8.1 billion USD according to a 2014 appraisal. The DIA campus is located in Detroit's Cultural Center Historic District, about 2 miles (3.2 km) north of the downtown area, across from the Detroit Public Library near Wayne State University.

Midtown Detroit is a commercial and residential district located along the east and west side of Woodward Avenue, north of Downtown Detroit, and south of the New Center area. The area includes several historic districts. In addition, it contains a residential area of some 14,550 people and covers 2.09 sq mi. The community area of neighborhoods is bounded by the Chrysler Freeway (I-75) on the east, the Lodge Freeway (M-10) on the west, the Edsel Ford Freeway (I-94) on the north, and the Fisher Freeway (I-75) on the south.