Diego Siloe (anglicized) or Diego de Siloé was a Spanish Renaissance architect and sculptor, progenitor of the Granadan school of sculpture. He developed the majority of his work in Andalusia.

The Granadan school of sculpture or Granadine school of sculpture—the tradition of Christian religious sculpture in Granada, Andalusia, Spain—began in the 16th century and constituted a clear tradition of its own by the 17th century. The extraordinary artistic activity of Renaissance Granada brought artists to that city from various regions of Spain and from other parts of Europe.