Diego Velázquez de Cuéllar was a Spanish conquistador and the first governor of Cuba. In 1511 he led the successful conquest and colonization of Cuba. As the first governor of the island, he established several municipalities that remain important to this day and positioned Cuba as a center of trade and a staging point for expeditions of conquest elsewhere. From Cuba, he chartered important expeditions that led to the Spanish discovery and conquest of the Aztec Empire.

Pedro de Alvarado was a Spanish conquistador and governor of Guatemala. He participated in the conquest of Cuba, in Juan de Grijalva's exploration of the coasts of the Yucatán Peninsula and the Gulf of Mexico, and in the conquest of the Aztec Empire led by Hernán Cortés. He is considered the conquistador of much of Central America, including Guatemala, Honduras, and El Salvador.