Dimitrios Kalapothakis was a Greek-American journalist, diplomat, translator, foreign correspondent, author, playwright, and founder of multiple Greek newspapers. He was a prominent member of the Evangelical church in Greece. He founded the Greek newspaper Empros. Dimitrios was from a prominent Greek American family and his father was the well-known author and doctor Michael D. Kalopothakis. Both his sisters became very important. Maria Kalapothakes was the first female doctor in modern Greece. His other sister Dafne Kalapothakes became a well-known archeologist. Their father owned a publishing company that published many different publications in Greece. Dimitrios and his father helped found the Hellenic Macedonian Committee. Dimitrios played a critical role in the Paris Peace Conference. He wrote an important book entitled Greece Before the Conference. The book attracted the attention of Eleftherios Venizelos who appointed Dimitrios Director of the Press Bureau, to the Ministry of Foreign Affairs for over eleven years.

Martha Hooper Blackler Kalopothakes was a 19th-century American missionary to Greece. She was also a journalist and translator. Kalopothakes died in 1871.