The Dipartimento delle Informazioni per la Sicurezza is a department of the Presidency of the Council of Ministers of Italy, instituted in 2007 as part of the reform of the Italian security services. The department is part of Sistema di informazione per la sicurezza della Repubblica. It is currently headed by Elisabetta Belloni, the successor to General Gennaro Vecchione.

The Presidency of the Council of Ministers is the administrative structure which supports the Prime Minister of Italy. It is thus the Italian equivalent of the Prime Minister's Office. It contains those departments which carry out duties invested in the office of the Prime Minister. Duties invested in the Italian executive government generally are not administered by the Presidency, but by the individual ministries.