Diss railway station is on the Great Eastern Main Line in the East of England, serving the market town of Diss, Norfolk. It is 94 miles 43 chains (152.1 km) down the line from London Liverpool Street and is situated between Stowmarket to the south and Norwich to the north. It is approximately 20 miles (32 km) south of Norwich. Its three-letter station code is DIS.

The Great Eastern Main Line is a 114.5-mile (184.3 km) major railway line on the British railway system which connects Liverpool Street station in central London with destinations in east London and the East of England, including Shenfield, Chelmsford, Colchester, Ipswich and Norwich. Its numerous branches also connect the main line to Southminster, Braintree, Sudbury, Harwich and a number of coastal towns including Southend-on-Sea, Clacton-on-Sea, Walton-on-the-Naze and Lowestoft.