Djerba, also transliterated as Jerba or Jarbah, is a Tunisian island and the largest island of North Africa at 514 square kilometers (198 sq mi), in the Gulf of Gabès, off the coast of Tunisia. Administratively, it is part of Medenine Governorate of this North African country. The island had a population of 139,544 at the 2004 census, which rose to 163,726 at the 2014 census. Citing its long and unique history, Tunisia has sought UNESCO World Heritage status protections for the island, and, in 2023, Djerba was officially designated a World Heritage Site.

The Gulf of Gabes, also known as Lesser Syrtis, contrasting with the Greater Syrtis in Libya, is a gulf on Tunisia's east coast in the Mediterranean Sea, off North Africa. The gulf roughly spans the coast from Sfax to Djerba. At the head of the gulf is the city of Gabès (Ghannouche) where the tides have a large range of up to 2.1 m at spring tides. Both Gabès and Sfax are major ports on the gulf, supporting sponge and tuna fisheries, with Gabès being the economic and administrative center.