The Domus Romana, stylized as the Domvs Romana, is a ruined Roman-era house located on the boundary between Mdina and Rabat, Malta. It was built in the 1st century BC as an aristocratic town house (domus) within the Roman city of Melite. In the 11th century, a Muslim cemetery was established on the remains of the domus.

Mdina, also known by its Italian epithets Città Vecchia and Città Notabile, is a fortified city in the Northern Region of Malta which served as the island's capital from antiquity to the medieval period. The city is still confined within its walls, and has a population of 250, but it is contiguous with the town of Rabat, which takes its name from the Arabic word for suburb, and has a population of over 11,000.