Dorchester County is a county located in the U.S. state of South Carolina. As of the 2020 census, the population was 161,540. Its county seat is St. George.

Saint George is a town in Dorchester County, South Carolina, United States. The population was 2,084 at the 2010 census, eight fewer than in 2000 census. It has been the county seat of Dorchester County since the county was formed from Colleton County in 1897.