Douala International Airport is an international airport located in Douala, the largest city in Cameroon and the capital of Cameroon's Littoral Region. With its 4 terminals and an average of 1.5 million passengers and 50,000 tonnes of freight per year, it is the country's busiest airport. The airport is managed and partly owned (34%) by the company Aeroport du Cameroon (ADC) which also manages all other 13 airports on Cameroonian soil.

The Cameroon Airlines Corporation, trading as Camair-Co, is an airline from Cameroon, serving as flag carrier of the country, a role which was previously filled by the now-defunct Cameroon Airlines. Camair-Co has its headquarters in the Immeuble La Rotonde in Douala, and operates out of Douala International Airport. The airline has never made a profit, and is struggling under the weight of its debts; most of its aircraft are currently grounded. The company slogan is French: L'étoile du Cameroun, The Star of Cameroon.